Unlimited Potential in CRISPR Diagnostic Technology

CRISPR detection of circulating cell-free Mycobacterium tuberculosis DNA in adults and children, including children with HIV: a molecular diagnostics study

Tuberculosis, a leading global cause of death, is often underdiagnosed in adults and children with HIV using sputum tests. Non-sputum assays are crucial for better diagnosis and treatment monitoring. This study explores ultrasensitive detection of M. tuberculosis cell-free DNA (Mtb-cfDNA) in blood for TB diagnosis and treatment response.