Mycobacterium avium complex (MAC)

The most common type of NTM bacteria in the U.S. is Mycobacterium avium complex (MAC). The great majority of NTM lung disease in the U.S. is caused by MAC. Two of the other more common NTM species that infect the lungs are M. abscessus and M. Kansas. 

For more information see our recent publication here.

The IntelliGenome team has developed a high-efficiency DNA polymerase-based and thermostable protein-enhanced CRISPR fluorescence detection system, and further developed an ultra-sensitive approach to detect MAC-NTM cell-free DNA (cfDNA) in blood samples, which is an isolation-free, multiplex recombinase polymerase amplification (RPA)-CRISPR detection assay, and a portable device to read POC test results.